CypRules: a rule-based P450 inhibition prediction server
نویسندگان
چکیده
منابع مشابه
The SMARTCyp cytochrome P450 metabolism prediction server
SUMMARY The SMARTCyp server is the first web application for site of metabolism prediction of cytochrome P450-mediated drug metabolism. AVAILABILITY The SMARTCyp server is freely available for use on the web at www.farma.ku.dk/smartcyp where the SMARTCyp Java program and source code is also available for download. CONTACT [email protected]; [email protected] SUPPLEMENTARY INFORMATION Supp...
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SUMMARY In this work we present WhichCyp, a tool for prediction of which cytochromes P450 isoforms (among 1A2, 2C9, 2C19, 2D6 and 3A4) a given molecule is likely to inhibit. The models are built from experimental high-throughput data using support vector machines and molecular signatures. AVAILABILITY The WhichCyp server is freely available for use on the web at http://drug.ku.dk/whichcyp, wh...
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The widespread interest in software process has led to the creation of a wide range of process-centered environments, each seemingly with a different process formalism. This eventuality presents us with two questions that we must address in order to build a flexible process component for incorporation into existing software environments. Such a component would be desirable, for example, to faci...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2015
ISSN: 1460-2059,1367-4803
DOI: 10.1093/bioinformatics/btv043